Guardian Antibodies™ are isolated from the first milk (colostrum) of immunized cows. Colostral antibodies are ideally suited for use as orally delivered human therapeutics. Guardian Antibodies™ have demonstrable advantages over other antibody sources:

Oral delivery: Guardian Antibodies™ are designed by nature for oral delivery. Newborn calves receive passive immunity by ingesting colostrum. The antibodies display exceptional stability to degradation in the stomach and small intestine.

Polyclonal: Guardian Antibodies™ are polyclonal. Each preparation of specific antibodies contains multiple specificities, leading to increased efficacy, particularly against complex targets.

Low cost: Colostrum is an extremely rich source of specific antibody. Approximately 50% of the protein in bovine colostrum is immunoglobulin and 1 kg of antibody can be sourced from a single cow.

Safe: There is a long history of human exposure to bovine immunoglobulin. Regular milk contains 1 – 1.5 g/L of bovine immunoglobulin, and the antibody is stable to standard pasteurization. The average individual has ingested more than 6 kg of bovine immunoglobulin by their 18th birthday. As a result, Guardian Antibodies™ are expected to have an exceptional safety profile.